Microbiome solutions

Microbiome solutions

The microbiome, a complex ecosystem of microorganisms inhabiting various environments, plays a fundamental role in biological processes. Understanding these intricate microbial communities is critical for advancing research across numerous fields. At OHMX.bio, we provide comprehensive microbiome analysis solutions, leveraging advanced sequencing technologies and robust bioinformatics to deliver high-resolution insights into microbial diversity, composition, and function.
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Human microbiome

Animal health

Environmental & agri-tech

Our approach to microbiome analysis

OHMX.bio offers a flexible and robust platform for microbiome analysis, tailored to address diverse research questions. We utilize cutting-edge sequencing technologies, including Oxford Nanopore long-read sequencing and high-throughput short-read platforms, to provide unparalleled resolution. Our methods enable:

Full-Length Amplicon Sequencing

Targeting marker genes like the full-length 16S rRNA (for bacteria and archaea) or ITS (for fungi) provides superior taxonomic resolution, enabling accurate identification of closely related species.

Shotgun Metagenomics

For a deeper functional understanding, we offer shotgun metagenomics, which sequences all DNA in a sample, allowing for the reconstruction of microbial genomes and the analysis of metabolic pathways and functional potential.

Metatranscriptomics

To understand active microbial processes, we can analyze the entire RNA content of a microbial community, revealing gene expression patterns and functional activity.

Our optimized workflows support high-throughput processing, capable of handling thousands of samples, ensuring efficient and scalable analysis for large-cohort studies.
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Human microbiome

The human microbiome is intimately linked to health and disease, influencing processes from digestion and immunity to neurological function. OHMX.bio supports clinical and research initiatives focused on the human microbiome by:

Characterizing Microbial Signatures

Identifying distinct microbial compositions associated with various health conditions, such as inflammatory bowel disease (IBD) or neurodegenerative disorders, to aid in early diagnosis and personalized interventions.

Assessing Therapeutic Impact

Monitoring changes in microbial communities in response to dietary interventions, probiotics, antibiotics, or other therapies.

Analyzing Diverse Sample Types

Our expertise extends to processing various human-derived samples, including fecal matter, skin swabs, oral rinses, and other liquid biopsies, ensuring comprehensive profiling of host-associated microbial ecosystems.

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Animal health & veterinary medicine

Microbiome analysis is increasingly vital in animal health, impacting livestock productivity, disease resistance, and overall animal well-being. OHMX.bio provides solutions for veterinary and agricultural research by:

Profiling Gut Microbiomes

Characterizing the gut microbiota of livestock and companion animals to understand its role in nutrient absorption, growth, and susceptibility to pathogens.

Investigating Disease Associations

Identifying microbial imbalances linked to animal diseases, informing diagnostic strategies and therapeutic approaches.

Supporting Nutritional Studies

Evaluating the impact of feed additives or dietary changes on the animal microbiome and its subsequent effects on health and performance.

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Environmental & agri-tech biotechnology

Microbial communities are fundamental to environmental processes, nutrient cycling, and sustainable agriculture. OHMX.bio offers advanced microbiome analysis for environmental and agri-tech applications, enabling:

Ecosystem Characterization

Understanding microbial diversity and function in various natural environments, such as soil, water, and industrial bioreactors.

Bioremediation & Pollution Monitoring

Identifying microbial populations involved in the degradation of pollutants or monitoring changes in microbial communities in response to environmental stressors.

Sustainable Agriculture

Exploring the role of plant-associated microbiomes in nutrient uptake, plant growth promotion, and disease resistance, contributing to more sustainable farming practices.

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Case studies

Case study 1: Enhancing biodiversity monitoring through long-read eDNA metabarcoding

Accurate biodiversity assessment is essential for environmental monitoring, yet resolving complex microbial communities remains challenging with conventional short-read sequencing approaches.

In the study “Unveiling Protist Composition and Diversity Patterns With eDNA Metabarcoding: Comparing Short- and Long-Read Approaches” (Skouroliakou, D.-I., Dupont, D.W.E., Vandenboer, Y. et al., Ecology and Evolution, 2026), advanced sequencing strategies were applied to analyze protist communities in the Belgian part of the North Sea. Through its expertise in long-read sequencing and data analysis, OHMX.bio contributed to enabling a more comprehensive view on biodiversity patterns.

By comparing short-read and long-read metabarcoding approaches targeting the 18S rRNA gene, the study demonstrated that while both methods align at higher taxonomic levels, long-read sequencing provides significantly improved resolution at species and sub-species level. This allows for more precise identification of ecologically relevant taxa.

Importantly, the long-read approach revealed taxa that were underrepresented or missed using short-read methods, resulting in a more accurate and complete representation of community composition.

This case study highlights how OHMX.bio supports environmental and ecological research by applying advanced sequencing technologies that unlock deeper biological insights and improve the reliability of biodiversity assessments.

Integrated bioinformatics for actionable insights

All microbiome projects at OHMX.bio are supported by our expert bioinformatics team. We develop custom analytical pipelines for taxonomic classification, functional profiling, statistical comparisons, and data visualization. Our integrated wet-lab and dry-lab approach ensures that the complex microbial data is transformed into clear, interpretable, and actionable insights, empowering your research across human, animal, and environmental applications.
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Let’s get in touch!

Are you curious about how we can work on your -omics challenges together? Fill out the form below!
Our experts will reply within 2 working days to freely discuss your omics project.

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