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Bioinformatics_ohmx

Ribo-seq bioinformatics

Ribo-seq bioinformatics
A standard bioinformatics package includes:
  • A full QC report on the raw Ribo-seq read data.
  • Preprocessing and cleaning of the Ribo–seq data.
  • Alignment to the reference genome (e.g. UCSC or IGV).
  • RPF (Ribosome protected fragments) offset calculation.
  • A full QC report on the aligned RPFs.
  • Counts at base resolution.
  • Summarized gene-level or transcript-level information in tabular format.
An advanced bioinformatics package includes*:
  • Standard bioinformatics package.
  • Translation Efficiency (if matching RNA-seq is available).
  • Differential analysis between the different groups + pathway enrichment analysis.
  • ORF (Open reading frame) delineation, start codon analysis.
  • Custom translation product database creation (for follow up MS-based proteomics).
  • Visual representation and reporting on the data analysis.

*Specific other analyses are possible per request.

RIBO-seq bioinformatics service

What do our customers say

  • "Thanks to the services of OHMX.bio, we were able to generate super high quality Ribo-seq data, which we would not have been able to generate ourselves."

    Kim De Keersmaecker

  • "We are very pleased with the way how the company is willing to do customized projects. The team takes responsibility for their work and results they provide. The communication with the team is very easy and fast. We wish the company to grow and flourish. Thank you for the excellent work!"

    Anya Goropashnaya

  • "We had an excellent experience working with OHMX.bio. Handling and processing of the samples were fast, the communication with the team was easy and the data produced are of outstanding quality. Definitely recommend it for Ribo-Seq analysis."

    Arnauld Blomme

  • “OHMX.bio has a broad expertise in multi-omics. Their laboratories are equipped with state-of-the-art analysis platforms and the company also has a strong bioinformatics team. So, outsourcing to one party with expertise in both RNA-seq, RIBO-seq & proteomics under one roof, made fully sense to us. Because of their strong know-how working with big data, they made a compilation & analysis of all our data over a large time scale, and this was impressive.”

    Glenn Pauwelyn (Head of Research and Development)

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Campus proeftuin – Building N1 Proeftuinstraat 86, 9000 Ghent