Element Biosciences AVITI sequencer

Our sequencing capabilities incorporate advanced platforms to generate high-quality omics data. The Element Biosciences AVITI Sequencer is a key component, providing a high-precision, high-throughput solution for next-generation sequencing (NGS) with increased read accuracy compared to mainstream sequencers. The system’s distinct chemistry and design contribute to accurate and comprehensive genomic data, particularly for applications requiring high fidelity.

Read accuracy and data quality

The Element Biosciences AVITI Sequencer demonstrates read accuracy exceeding 90% at Q40. This level of precision is relevant for applications where subtle sequence variations are critical for analysis. The data produced by the AVITI system supports:

Enhanced Variant Detection

Facilitates the reliable identification of single nucleotide variants (SNVs), small insertions/delations (indels), and other genetic alterations, including those present at low allele frequencies, which is crucial for identifying disease-causing mutations in rare genetic disorders or somatic variants in cancer.

Reduced Error Rates

The inherent accuracy of the system contributes to lower sequencing error rates, which can streamline downstream data processing and reduce the need for extensive validation of potential artifacts, particularly important for clinical diagnostic pipelines.

Robust Downstream Analysis

Data generated with high fidelity provides a solid foundation for complex bioinformatics analyses, supporting confidence in scientific interpretations and enabling more reliable conclusions from multi-omic studies.

OHMX.bio - Innovative omics solutions
Element Biosciences AVITI sequencer
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Throughput and application versatility

In addition to its accuracy, the AVITI Sequencer offers significant throughput, making it adaptable for both targeted and large-scale sequencing projects. Its capabilities support a range of applications across various research domains:

Genomic Profiling

Applicable for whole-genome sequencing (WGS) and whole-exome sequencing (WES), providing a detailed view of genetic variation across the genome or exome, including the resolution of complex genomic regions and structural variants for de novo assemblies.

Targeted Sequencing

Supports focused analysis of specific genomic regions, enabling deep coverage for genes or loci of interest, valuable for in-depth analysis of specific disease panels or validation of CRISPR/Cas9 edits.

Biomarker Identification and Validation

The precision of the AVITI system is beneficial for identifying and validating genetic biomarkers in areas such as oncology and inherited diseases, contributing to the development of precision medicine strategies.

Clinical Research

Its accuracy and reliability contribute to its utility in clinical sequencing applications where data integrity is a primary consideration for patient diagnostics and personalized treatment planning.

Integration within OHMX.bio's workflow

The Element Biosciences AVITI Sequencer is integrated into OHMX.bio’s comprehensive wet-lab and dry-lab workflows. Our team utilizes the AVITI’s capabilities to optimize library preparation, execute sequencing runs, and perform bioinformatics analysis. This integration aims to ensure efficient data generation and provide actionable data tailored to specific project requirements.
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Our publications using the Element Biosciences AVITI sequencer

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