OHMX.bio_Long-read sequencing

Long-read sequencing

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Instruments available

Setups offered

Sample types

Adaptive sampling

What is long-read sequencing?

Long-read sequencing is a next-generation sequencing approach capable of producing reads that span ~10–100 kb of base pairs in length (longer possible). It is particularly useful for resolving structural variants, characterizing complex regions, and assembling genomes without fragmentation.
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Instruments available

ONT GridION

ONT P2 Solo

ONT P2 Solo

ONT QLine

ONT QLine

Partner access

OHMX.bio also offers sequencing services via established partners using:    
    • PacBIO Revio
 

Setups offered

As a certified provider, OHMX.bio supports all Oxford Nanopore Technologies (ONT) setups:

Genomic DNA Sequencing

Whole-genome sequencing, targeted sequencing, structural variant analysis.

Direct RNA Sequencing

Sequencing of native RNA molecules including modified bases without the need for reverse transcription or amplification.

cDNA Sequencing

Reverse transcription-based sequencing for enhanced throughput and quantification of gene expression.

Amplicon Sequencing

High-depth sequencing of specific regions, ideal for variant detection in targeted assays.

Metagenomic Sequencing

Characterization of microbial communities without the need for culture.

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OHMX.bio - Innovative omics solutions

Sample types

OHMX.bio accepts a broad range of sample types. For an overview of accepted materials and preparation guidelines, see sample requirements page.

Advantages

  • Long contiguous reads
  • Real-time sequencing output
  • No amplification needed (for direct RNA)
  • Detection of structural variants and isoforms
  • Capable of detecting modified bases

Common Applications

  • Full-length transcript sequencing
  • Genome assembly
  • Structural variant detection
  • Isoform resolution
  • Modified base detection
  • Microbiome profiling (e.g., full-length 16S)
  • Plasmid validation
  • Quality control of biologics

Adaptive sampling

Adaptive sampling is a targeted in silico sequencing method unique to nanopore sequencing technology. It uses real-time signal analysis to selectively enrich or deplete specific regions of interest during the sequencing run. By analyzing the electrical signal from the DNA molecule as it enters the nanopore, the system can accept or reject molecules based on alignment to a user-defined reference. This allows targeting specific genomic regions, increasing coverage of regions of interest while saving sequencing resources.

Advantages
  • No need for custom capture kits
  • Reduced sequencing of irrelevant regions
  • Maximized data output on target sequences
  • Flexible and easily adjustable targeting strategy

OHMX.bio has extensive experience in setting up and running adaptive sampling experiments for a range of research and development applications.
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Partner with OHMX.bio

Whether you are conducting fundamental research, developing novel therapeutics, or advancing clinical diagnostics, OHMX.bio’s lab- and bio-IT solutions are here to support your goals. Our commitment to innovation, quality, and client success makes us the ideal partner for generating advanced biological insights.
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Let’s get in touch!

Are you curious about how we can work on your -omics challenges together? Fill out the form below!
Our experts will reply within 2 working days to freely discuss your omics project.

Our publications using long-read sequencing solutions

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